This artwork is known as "The Demon Omatsu Murders Shirosaburō in the Ford" From the series A New Selection of Eastern Brocade Pictures (Shinsen azuma nishikie).
The original work is at the Philadelphia Museum of Art
Tsukioka Yoshitoshi is widely recognized as the last great master of the ukiyo-e genre of woodblock printing and painting. He is also regarded as one of the form's greatest innovators. By the end of his career, Yoshitoshi was in an almost single-handed struggle against time and technology. As he worked on in the old manner, Japan was adopting Western mass reproduction methods like photography and lithography. Nonetheless, in a Japan that was turning away from its own past, he almost singlehandedly managed to push the traditional Japanese woodblock print to a new level, before it effectively died with him. ¹
¹Wikipedia. Accessed March 25, 2016. https://en.wikipedia.org/wiki/Yoshitoshi.